Tonic-clonic seizure, also known as grand mal seizure, is
characterized by an abrupt loss of consciousness accompanied by body stiffening
(tonic phase) followed by shaking or jerking of the limbs (clonic phase).
Currently available treatment options such as Valproate, Levetiracetam and
Phenytoin aim to control the spread of excessive or irregular neuronal activity
in the brain which causes seizures. However, these drugs have side effects and
may not be effective in all cases. This has propelled research into developing
more efficacious and safe drugs for tonic-clonic seizure treatment.
The Global Tonic-clonic
Seizure Market is estimated to be valued at US$ 3.1 billion in 2024 and is
expected to exhibit a CAGR of 4.5% over the forecast period 2024-2029.
Key Takeaways
Key players operating in the tonic-clonic seizure treatment are UCB,
Pfizer, Johnson and Johnson, Abbott, GlaxoSmithKline and Sunovion
Pharmaceuticals.
Growing prevalence of epilepsy disorders globally is a major factor driving the
demand for tonic-clonic seizure treatment drugs. According to the World Health
Organization (WHO), around 50 million people worldwide have epilepsy with close
to 80% of them living in developing nations.
Technological advancements in the field of neuroscience and central nervous
system drugs have enabled researchers to gain better understanding of the
disease pathology and design drugs that selectively target epileptic circuits
and signalling pathways in the brain linked to seizure generation. This has
opened up possibilities for developing next-generation anti-seizure
medications.
Market Trends
Increasing focus on developing oral anti-seizure drugs: Currently most
anti-seizure drugs available are generic first generation drugs. However, second
generation anti-seizure drugs being developed have better tolerability and
efficacy profiles.
Rise in novel drug delivery technologies: Newer technologies such as
nanomedicine are enabling development of drugs with improved bioavailability,
reduced side effects and targeted delivery to the brain. This is fast emerging
as an attractive avenue for industry players.
Market Opportunities
High unmet needs in developing countries presents significant opportunity
for low-cost generic anti-seizure drugs.
Focus on precision medicines and personalized treatment approaches tailored to
individual patient profiles based on clinical as well as genetic/molecular
factors offers a lucrative long-term opportunity.
Impact of COVID-19 on Tonic-clonic
Seizure Market Growth
The COVID-19 pandemic has adversely impacted the growth of the tonic-clonic
seizure market. During the peak of the pandemic in 2020, most countries went
under lockdown which restricted the movement of people. This led to decrease in
number of patient visits to neurologists for treatment and diagnosis of
tonic-clonic seizures. As hospitals focused majorly on treatment of COVID-19
patients, resources were diverted from other therapies and surgeries. This
resulted in postponement of non-urgent procedures and elective surgeries for
patients suffering from tonic-clonic seizures.
However, with rapid vaccination drives in 2021, several economies were able to
lift lockdown restrictions and normalcy was restored in healthcare services.
This helped the tonic-clonic seizure market to bounce back. Additional funding
by governments globally for research in seizure treatment aided market growth.
Teleconsultations also helped patients to continue their treatment plan and
follow-ups with neurologists remotely during lockdowns. In the coming years,
growing awareness about epilepsy management and availability of innovative
drugs are expected to drive further growth of this market.
Concentration of Tonic-clonic Seizure
Market in terms of Value
The United States accounts for the largest share of the global tonic-clonic
seizure market in terms of value. This is primarily due to high prevalence of
epilepsy in the country and availability of advanced treatment options.
According to CDC estimates, over 3 million people in the US suffer from
epilepsy. Favorable reimbursement policies for anti-seizure medications also
support high demand. Europe is the second largest regional market driven by
rising geriatric population and increasing awareness. Countries like Germany,
United Kingdom and France have emerged as major revenue generators. The market
is also growing significantly in Asia Pacific region supported by improving
healthcare infrastructure and economic growth in nations like China and India.
Fastest Growing Region in Tonic-clonic
Seizure Market
Asia Pacific region is poised to witness the fastest growth in the
tonic-clonic seizure market during the forecast period. This is attributed to
growing patient pool, rising healthcare spending, lower treatment costs and
increasing focus of international players on emerging Asian economies.
Initiatives by governments to spread awareness about epilepsy management also
supports market expansion. In addition, with improving standards of living,
people are able to afford advanced anti-seizure drugs. Countries like China,
India and South Korea are expected to drive the market growth in Asia Pacific
region.
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What
Are The Key Data Covered In This Tonic-clonic Seizure
Market Report?
:- Market
CAGR throughout the predicted period
:- Comprehensive
information on the aspects that will drive the Tonic-clonic Seizure's growth
between 2024 and 2031.
:- Accurate
calculation of the size of the Tonic-clonic Seizure and its contribution to the
market, with emphasis on the parent market
:- Realistic
forecasts of future trends and changes in consumer behaviour
:- Tonic-clonic
Seizure Industry Growth in North America, APAC, Europe, South America, the
Middle East, and Africa
:- A
complete examination of the market's competitive landscape, as well as
extensive information on vendors
:- Detailed
examination of the factors that will impede the expansion of Tonic-clonic
Seizure vendors
About Author:
Ravina Pandya, Content Writer, has a strong foothold
in the market research industry. She specializes in writing well-researched
articles from different industries, including food and beverages, information
and technology, healthcare, chemical and materials, etc. (https://www.linkedin.com/in/ravina-pandya-1a3984191)
*Note:
1. Source:
Coherent Market Insights, Public sources, Desk research
2. We
have leveraged AI tools to mine information and compile it
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